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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Diana Chang

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Open access Oct 2026

GEMS (GWAS Effect Mechanisms via Sequence-to-Function): Unveiling cell type-specific mechanisms for GWAS variants

Genome-wide association studies (GWAS) have linked thousands of loci to common diseases, yet for non-coding variants, which constitute the vast majority of the signal, the cell types and states through which individual risk variants act remain largely unknown. Here, we develop GEMS (GWAS Effect Mechanisms via Sequence-...

Xiao-Man Xie, Sheng Qian, Diana Chang et al. · 0 citations

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