Microstructural Characterization of Functional Network-Based Neurodegeneration in Multiple Sclerosis Using High-Gradient Diffusion MRI.
BACKGROUND AND PURPOSE Neurodegeneration is a key component of clinical disability in multiple sclerosis (MS). However, the underlying mechanism of localized gray matter (GM) atrophy in MS remains unknown. More recently, a network-based etiology has been postulated, which may be associated with clinical progression. Th...