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Author

Di-Wei Zheng

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Review Oct 2026

Reprogramming the therapeutic fate of living biotherapeutic products for intestinal diseases via biomaterials.

Live biotherapeutic products (LBP) hold great promise for the treatment of intestinal diseases such as inflammatory bowel disease and colorectal cancer, owing to their unique abilities to modulate the gut microbiota, regulate host immunity, and influence drug metabolism. However, the use of natural strains remains cons...

Xi-Yu Cheng, Yun-Qi Yang, Hai-Tao Ding et al. · 0 citations
Open access Jul 2026

SPgen: Proteome-wide Spatial Proteomics generation using multi-modality foundation models

SPgen integrates protein sequences, functional annotations, transcriptomic profiles, and spatial information to learn transferable representations that enable inference beyond experimentally profiled proteins, and accurately reconstructs measured spatial patterns, reduces measurement noise, and enables proteome-wide sp...

Jia-Chen Li, Kai-Yuan Yang, Qiaoling Che et al. · 0 citations

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