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Review Open access Sep 2026

Spatial proteomics: technical evolution and applications in cancer research

Spatial proteomics is reshaping tissue-based cancer research by linking protein expression to cellular identity, tissue architecture and clinical behavior. Conventional proteomics has provided powerful tools for protein identification and quantification, but most bulk workflows erase the spatial relationships that defi...

Xiao-Xiao Tian, Di Huang, Jia-Xiang Hu · 0 citations
Review Open access Sep 2026

Interactions between circular RNAs (circRNAs) and the Hippo pathway in cancer

This review delves into the complex roles of circRNAs in Hippo pathway modulation and their implications for cancer progression, and aims to elucidate the mechanisms of circRNA-Hippo interactions comprehensively and translate these insights into clinical applications.

Peng-Hui Li, Di Huang, Xin-Yu Gu · 0 citations
Aug 2026

T Cell-associated Co-expression Module Genes as Prognostic Biomarkers and Predictors of Immunotherapy Response in Head and Neck Squamous Cell Carcinoma.

INTRODUCTION The important roles of T cells in tumor progression support the development of a T cell-associated prognostic model for Head and Neck Squamous Cell Carcinoma (HNSCC). METHODS The single-cell RNA-seq (scRNS-seq) data from GSE181919 were processed via the Seurat package for quality control and cell annotat...

Qing-Miao Shi, Zhen-Zhen Qi, Bingyang Shang et al. · 0 citations

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