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Author

Di Hu

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Open access Oct 2026

Disassembly of mitochondrial cristae architecture drives neurodegeneration in Huntington’s disease

Mitochondrial dysfunction is a key feature of many neurodegenerative diseases, including Huntington’s disease (HD), yet the initiating cellular lesion that links the disease-causing protein, mutant huntingtin (mtHtt), to organelle failure and neuronal degeneration remains unclear. Using complementary in vi...

Yu-Tong Shang, Rihua Wang, Di Hu et al. · 0 citations

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