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Jul 2026
Atherosclerosis destabilizes regulatory T cells (Tregs) resulting in multiple families of exTregs
Qingkang Lyu, Yan Wang, Anusha Bellapu et al.
· bioRxiv · 0 citations
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Jul 2026
Distinct Treg subsets in human peripheral blood are defined by unique transcriptomic signatures 2252633
Regulatory CD4+ T cells (Tregs) are critical for maintaining tolerance to self. Chronic inflammation can cause Treg instability which is defined by loss of CD25 and the lineage-defining transcription factor FOXP3, resulting in exTreg cells. To better understand the factors driving Treg to exTreg conversion...
Smriti Parashar, P. Roy, Mohammad Oliaeimotlagh et al.
· Journal of Immunology · 0 citations