Oct 2026
Antiviral immunity via telomerase-like reverse transcription in bacteria.
Stephen Tang, Josephine L. Ramirez, Qi-Xiang He et al.
· Nature · 0 citations
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Oct 2026
Reverse transcribed ssDNA derepresses translation of a retron antiviral protein.
Retrons are bacterial immune systems that prevent phage propagation by initiating a toxic response within infected hosts. Previously characterized retrons produce abundant multicopy single-stranded DNA (msDNA) by reverse transcription, which acts as an antitoxin in the absence of phage. However, we describe here a non-...
Karen Zhang, Matías Rojas-Montero, Darshini Poola et al.
· Molecules and Cells · 0 citations