Author

Dennis Gankin

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Open access Jul 2026

Leveraging multiplicity in biologically informed neural networks to uncover disease heterogeneity

Analysis of the space of BINN explanations can turn multiplicity into a tool for studying complex disease mechanisms, and across 100 replicate BINNs for type 2 diabetes, the authors find distinct solution clusters prioritizing either inflammatory or hepatic-metabolic pathways.

Dennis Gankin, P. Beltrao · bioRxiv · 0 citations