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Author

Deng-Yue Sun

2 papers indexed here

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Aug 2026

Hydroxyethyl starch serves as a superior vehicle for colon-targeted delivery of indole-3-acetic acid to enhance therapeutic efficacy against colitis.

Indole-3-acetic acid (IAA), a crucial tryptophan-derived metabolite, exerts anti-inflammatory and immunomodulatory effects primarily through activation of aryl hydrocarbon receptor (AhR) and modulation of gut immune homeostasis, providing a mechanistic rationale for its use in colitis. Colon-targeted delivery of IAA to...

Lin Tian, Qian Gong, Wen-Shan Yang et al. · 1 citation
Sep 2026

Engineering a thermostable MHET-active esterase through active-site compaction for efficient dual-enzyme PET depolymerization.

Efficient enzymatic recycling of polyethylene terephthalate (PET) is frequently hindered by the accumulation of mono-(2-hydroxyethyl) terephthalate (MHET), a soluble intermediate that competitively suppresses PET hydrolase activity. Although MHET-hydrolysing enzymes can overcome this limitation, these enzymes often exh...

Li-Na Qiu, Jie Zhang, Yan-Zi Sun et al. · 0 citations

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