Aug 2026
Systematic identification of species-specific allosteric sites in bacterial glycolytic enzymes: Hexokinase, phosphoglucose isomerase, phosphoglycerate kinase, and enolase.
Across all four glycolytic enzymes, interface-localized pockets consistently emerged as promising candidate regulatory regions, suggesting that protein-protein interfaces may represent valuable targets for allosteric modulation.
Defne Alnıgeniş, Florihana Brina, Ilknur Kocal et al.
· Biochimica et Biophysica Act... · 1 citation