Deborah L. Caldwell

Characterisation of drug loaded insoluble polymeric matrices prepared by hot melt extrusion technology for drug delivery applications.

The main aim of this research was to manufacture and characterise the physiochemical, rheological and drug release properties of drug loaded insoluble matrices prepared by HME technology, to provide a deeper understanding of the mechanisms which affect drug release from hot melt extruded solid dosage forms. Polymethacr...