Acetaminophen (APAP) overdose is a major cause of acute liver failure (ALF). We previously observed activation of liver kinase B1 (LKB1) in non-surviving patients with APAP-induced ALF. Thus, we hypothesized LKB1 is detrimental in APAP hepatotoxicity. To test our hypothesis, we overdosed hepatocyte-specific LKB1 knocko...
Debasree Bhadra, Jenna S. Caswell, Kathryn L. Smith et al.· Toxicological Sciences· 0 citations
This review provides a comprehensive overview of the key analytes employed in liquid biopsy, including circulating tumor DNA, circulating tumor cells, microRNAs, extracellular vesicles, and protein biomarkers with particular emphasis on their translational relevance in breast cancer.
Pritam Saha Podder, Debasree Bhadra, Canio Martinelli et al.· Exploration of Targeted Anti...· 0 citations
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