#protein folding
Aug 2026
Oligomerized receptor binding domain blocks pan-sarbecovirus infection via enhanced avidity to host receptor.
HRBD demonstrated potent and broad-spectrum inhibition against Pangolin-CoV, SARS-CoV, SARS-CoV, SARS-CoV-2, and its variants, lowering the half-maximal inhibitory concentration (IC50) by approximately 1000-fold compared to the monomeric RBD.
Jintao Zou, Lingyu Su, Jiansheng Lu et al.
· Antiviral Research · 0 citations