P53 promotes DOX resistance by suppressing HIF‐1α/P300‐mediated TFRC transcription and TFRC‐dependent ferroptosis, highlighting the P53/P300/HIF‐1α/TFRC axis as a potential therapeutic target in DOX‐resistant breast cancer.
Xiao-Jie Yu, L. Yao, Shu-Chun Zhang et al.· The FASEB Journal· 0 citations
The nomograms showed good internal discrimination and may support individualized prognostic assessment once initial treatment information is available, and 5-year estimates should be interpreted cautiously given the median follow-up of 27 months.
Overall, curcumin suppresses breast cancer progression by upregulating miR-181b and downregulating Bcl-2 and downregulating Bcl-2 in a dose-dependent manner.
Feng-Lin Cai, Xue-Na Geng, Hang Su et al.· Boletin Latinoamericano y de...· 0 citations
A previously unrecognized transcription‐ubiquitination cascade that modulates Hippo signaling and contributes to breast cancer progression is revealed, highlighting this axis as a candidate therapeutic vulnerability that warrants further validation for limiting metastasis.
An Xu, Xiang-nan Xu, Xiao Huang et al.· Advancement of science· 0 citations
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