Author

De-Run Kong

2 papers indexed here

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Oct 2026

Mannose attenuates CCl4-induced liver fibrosis by reducing oxidative stress through AMPK-dependent NRF2 signaling.

Mannose, a naturally occurring hexose, has been implicated in the regulation of metabolism and inflammation. Although emerging evidence suggests its therapeutic potential in liver diseases, the mechanisms by which mannose modulates liver fibrosis, particularly in relation to oxidative stress, remain poorly defined. Thi...

Qian Hu, He-Jiao Zhang, Shan-Fei Tian et al. · Journal of Nutritional Bioch... · 0 citations

Open access Oct 2026

Tangeretin Targets Macrophage M1 Polarization to Alleviate Liver Injury in a Murine Model of Hepatic Sinusoidal Obstruction Syndrome.

Hepatic sinusoidal obstruction syndrome (HSOS) is a life-threatening liver microvascular disorder characterized by hepatic sinusoidal endothelial cells (HSECs) injury, for which safe and effective pharmacological treatments are currently lacking. Tangeretin (TAN), a natural polymethoxylated flavone, exhibits anti-infla...

Fu-Min Zhang, Cheng Zhu, Xing-Yu Li et al. · Phytotherapy Research · 0 citations