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De-Kai Liu

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Review Open access Oct 2026

Spatial and single-cell insights into the prostate cancer microenvironment: overcoming immunotherapy resistance through multidimensional strategies

Despite breakthroughs in immune checkpoint inhibitors (ICIs) across various malignancies, prostate cancer (PCa), particularly metastatic castration-resistant prostate cancer (mCRPC), has shown limited responses to ICIs. This pervasive primary resistance is fundamentally driven by the canonically “immune-cold” and highl...

De-Kai Liu, Jun-Liang Tang, Yi-Wei Jiang et al. · 0 citations

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