Integrative multi-omics landscape and diagnostic-therapeutic modelling of steatohepatitic hepatocellular carcinoma.
BACKGROUND Steatohepatitic hepatocellular carcinoma (SH-HCC) is a distinct subtype of hepatocellular carcinoma with poorly defined molecular features and limited diagnostic and therapeutic strategies. OBJECTIVE This study aimed to delineate its multi-omics landscape, develop non-invasive diagnostic tools and identify...