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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Davide Mazzeo

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Open access

An Electroporation-Based Protocol for Ex Vivo Base Editing: From Design to Quantitative Assessment.

This chapter provides a practical protocol for base editing by electroporation by electroporation in adherent and suspension stem cells and details essential steps for cell handling and recovery, followed by standard readouts.

Irene Peña-Gutiérrez, Davide Mazzeo, A. Bassons-Bascuñana et al. · 0 citations
Open access Aug 2026

Adenine base editing correction of LMNA c.745C>T (p.R249W) in congenital muscular dystrophy myoblasts improves cellular phenotype while revealing deleterious p.L248P bystander effects

These results demonstrate that ABE can effectively target the LMNA c.745C>T mutation but also reveal the significant impact of bystander edits on cellular physiology, underscoring the necessity of precise editing technologies to ensure both efficacy and safety in future clinical translation.

M. Santafé, I. Hernández, D. Mazzeo et al. · 0 citations

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