David Sant

The gut-brain-vascular axis: converging neuroinflammatory and hypertension-mediated pathways from gut dysbiosis to cognitive decline

Hypertension and cognitive decline are major public health burdens, and both have been associated with gut microbiome dysbiosis. We propose the gut-brain-vascular axis as a testable synthesis in which dysbiosis may contribute to cognitive decline through two converging routes: direct neuroinflammatory signaling and hyp...