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David Ming Segura

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Preprint Aug 2026

Bi-semantic Chemical Embedder for Joint Representation Learning of SMILES and Natural Language

Transformer models have revolutionized natural language processing (NLP), and text-based molecular representations like SMILES have successfully extended these architectures to chemistry. However, domain-adaptive pre-training often causes models to overfit to chemical syntax, catastrophically forgetting their foundatio...

David Ming Segura, Jeremy Goumaz, Joshua W. Sin et al. · 1 citation

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