David Livingstone Alves Figueiredo

Absolute Microbial Abundance and Causal Inference as Foundations for a One Health Roadmap in Colorectal Cancer Diagnostics

Abstract The rising global incidence of colorectal cancer (CRC) necessitates a shift toward a functional understanding of the intestinal ecosystem. Although the microbiome is implicated in oncogenesis, most studies rely on relative abundance metrics, which are vulnerable to compositionality bias. To address this limita...