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Author

David Kwon

2 papers indexed here

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Sep 2026

Abstract B058: Combining RAS and splicing inhibition in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest cancer types in the United States, with over 90% of tumors driven by oncogenic KRAS. Several KRAS inhibitors have demonstrated promising preclinical or early clinical efficacy; however, their therapeutic benefit is limited by the emergence of acquired...

Saurabh Mandal, M. Bharmal, Swathi Sridhar et al. · 0 citations
Sep 2026

Abstract B031: Spatial profiling reveals distinct tumor and myeloid ecosystems across lung and liver metastases in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDA) exhibits marked organotropism, with the liver and lung representing the most common sites of metastatic recurrence. While PDA most often metastasizes to the liver, patients with only lung metastasis have a better overall prognosis, highlighting a role for both tumor-intrinsic pr...

E. Lasse-Opsahl, Daksh Thakkar, Julie M. Clark et al. · 0 citations

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