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David J Friedman

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Sep 2026

New ideas about mechanism in APOL1 kidney disease.

Apolipoprotein L1 risk variants contribute to high rates of kidney disease among individuals of African ancestry. These gain-of-function variants cause toxicity to kidney cells, but the mechanism of injury is not clear. Many theories have been proposed, yet the field has not arrived at a consensus. Kim et al. make a co...

David J Friedman, Martin R. Pollak · 0 citations

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