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Author

D. Einstein

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3 papers indexed here

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Oct 2026

Progression to castration-resistance and metastatic disease following androgen deprivation therapy for biochemical recurrence after prostate cancer surgery.

BACKGROUND Biochemical recurrence after radical prostatectomy for localized prostate cancer impacts nearly one in four patients. While androgen deprivation therapy (ADT) is used in this setting, its impact on metastatic disease outcomes remains unclear in contemporary population-based cohorts. METHODS We performed a...

G. Raster, David A. Elliott, Ellen Hu et al. · 0 citations
Open access Aug 2026

A Phase II Study of Berzosertib in Combination with Carboplatin Compared with Docetaxel with Carboplatin in Metastatic Castration-Resistant Prostate Cancer

The combination of the ATR inhibitor berzosertib with carboplatin demonstrated a lower ORR and more frequent ≥ grade 3 TrAEs compared with docetaxel + carboplatin in this heavily pretreated, biomarker-unselected mCRPC population.

A. Choudhury, C. Zhong, Wan-Ling Xie et al. · 0 citations
Open access Aug 2026

Tumor-adjacent B cell infiltration stratifies recurrence risk in localized prostate cancer

Background: Biochemical recurrence (BCR) occurs in 20-40% of men after radical prostatectomy. Existing postoperative recurrence risk tools based on PSA and pathology are clinically useful but show only moderate and variable discrimination, highlighting the need for biomarkers that improve risk stratification and conseq...

B. Wang, S. Mukherjee, A. Baj et al. · 0 citations

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