Open access
Jul 2026
Cryo-EM insights into isoform-specific properties of the IP3R2 channel
Cryo-EM structures of human IP3R2 are determined and mechanisms of IP3R2 activation and subtype-specific regulation are revealed, providing a framework for understanding isoform-dependent Ca2+ signaling.
M. R. Baker, Xiao-Xuan Lin, G. Fan et al.
· Nature Communications · 0 citations