David H. Johnson

Membrane Phase, Charge, and Curvature Regulate α-Synuclein Binding Dynamics.

α-Synuclein (αSyn) is an intrinsically disordered protein whose interactions with lipid membranes are central to both its physiological function and its role in synucleopathies. While membrane charge, phase, and curvature are each known to influence αSyn binding, these properties are typically examined independently, l...