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Author

David Giron-Villalobos

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Review Open access Oct 2026

Role of the urobiome in urinary tract infections: current knowledge and research prospects.

Urinary tract infections (UTIs), particularly cystitis, are among the most common bacterial infections worldwide, with a disproportionate burden on adult female individuals, who often have recurrence. The discovery of the urobiome, a low microbial biomass community in the urinary tract, has transformed our understandin...

Marleen D. Hekker, Adam J. Bindas, Freya Darling Eriksen et al. · 0 citations
Open access Aug 2026

Metabolite co-variation networks reveal keystone functions and an emergent pathogen state in the human urobiome

PhenoRewire, a network-based framework that quantifies how metabolite co-variation is rewired between biological states using untargeted metabolomics data, is developed and applied to an induced pluripotent stem cell (iPSC) urothelial organoid-derived barrier co-cultured with synthetic urobiome communities as a model o...

L. della Vedova, Adam J. Bindas, Mariana Teixeira Dias et al. · 0 citations

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