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Author

David G. Drubin

2 papers indexed here

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Open access Oct 2026

Mechanical regulation of endocytosis by protein droplet capillary forces

Clathrin-mediated endocytosis (CME) is the primary pathway for internalization of extracellular and membrane cargo in eukaryotic cells. It is characterized by a patch of the plasma membrane invaginating and pinching off to generate a cytoplasmic vesicle. Recently, experimental evidence has begun to accumulate in suppor...

M. A. Ferrin, D. Mokbel, M. Mokbel et al. · 0 citations
Open access Sep 2026

Phosphoregulation of hierarchical protein condensate formation during clathrin-mediated endocytosis

The sequential assembly of over 50 proteins during clathrin-mediated endocytosis (CME) is well documented in yeast. However, the mechanisms governing this ordered recruitment remain poorly understood. Biomolecular condensation is proposed to orchestrate CME, but defining biophysical parameters in vivo remains challengi...

Yi-Di Sun, Andrew Wong, Ge-An Hu et al. · 0 citations

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