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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

David F. Savage

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Open access Apr 2026

Polyphosphate acts as an architectural regulator of carbon fixation and nucleoid structure in cyanobacteria

It is found that polyP functions as a spatially organized regulator of the photosynthetic cytoplasm in Synechococcus elongatus and is identified as an architectural integrator that couples chromosome organization, metabolic compartmentalization, and photosynthetic fitness.

Claire E. Dudley, Daniel J. Foust, David F. Savage et al. · 0 citations
Open access Jul 2026

Activity and specificity trade-offs in adenine base editors

This work found that the ABEs were fully described by the single dimension of intrinsic deaminase activity with no evidence for independent specialization with respect to local sequence context, editing window width, RNA editing, RNA editing, or genotoxicity.

Maria Lukarska, L. Oltrogge, Hunter M. Nisonoff et al. · 1 citation
Open access Aug 2026

Reprogramming Cas9 PAM Recognition for Allele-Specific Editing

A yeast selection platform is developed to engineer Cas9 with re-specified activity across multiple additional non-canonical PAMs in yeast, further demonstrating its utility as a general and programmable framework for expanding the therapeutic reach of precision genome editing.

Julia Tartaglia, Vivian Nguyen, John James Desmarais et al. · 0 citations

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