Author

David A. Isenberg

2 papers indexed here

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Aug 2026

Clinical characteristics and long-term outcomes in SLE-myositis overlap syndrome: a controlled retrospective cohort study.

OBJECTIVES Systemic lupus erythematosus (SLE) with concurrent inflammatory myositis (IIM) has a distinct clinical phenotype, yet its impact on long-term outcomes has been poorly defined. We aimed to determine the risk of mortality, malignancy, and severe renal disease in a large SLE cohort stratified by the presence of...

G. Uzun, David A. Isenberg · Rheumatology · 0 citations

Review Open access Sep 2026

Targeted therapies in systemic lupus erythematosus: mechanistic insights and clinical evidence from phase II and III trials

A systematic review of multicentre, randomised, placebo or standard of care-controlled phase II and phase III clinical trials investigating novel targeted and biological therapies in patients with SLE finds emerging therapies directed at specific immune pathways offer the potential to reduce disease activity, minimise...

J. Abrantes, Marina Dueñas-Ochoa, R. Meidan et al. · Frontiers in Lupus · 0 citations