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Author

Darshini Poola

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Oct 2026

Reverse transcribed ssDNA derepresses translation of a retron antiviral protein.

Retrons are bacterial immune systems that prevent phage propagation by initiating a toxic response within infected hosts. Previously characterized retrons produce abundant multicopy single-stranded DNA (msDNA) by reverse transcription, which acts as an antitoxin in the absence of phage. However, we describe here a non-...

Karen Zhang, Matías Rojas-Montero, Darshini Poola et al. · 0 citations

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