46 Anti-tumour immune responses in melanoma brain metastases require cDC1 population and the extracranial tumour
Brain metastases (BrM) are associated with poor prognosis, partially due to the specialized immune-microenvironment in the brain. Our previous study demonstrated that intracranial tumours alone are poorly immunogenic, but simultaneous presence of a subcutaneous tumour, mimicking the extracranial disease observed...