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Author

Daria Semicheva

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Open access Aug 2026

Insertion-Site Proximity to AAV Inverted Terminal Repeats Increases Plasmid Recombination

Adeno-associated virus (AAV)-based massively parallel reporter assays (MPRA) have become an important platform for large-scale functional characterization of regulatory DNA elements. However, plasmids carrying AAV inverted terminal repeats (ITRs) are intrinsically unstable during propagation in Escherichia coli, potent...

Maxim Makarenko, Daria Semicheva, Veniamin Fishman · 0 citations

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