Agmatine as the initiating substrate for aspartate semialdehyde-dependent bacterial spermidine biosynthesis.
The substrate specificity of the B. fragilis and C. leptum enzymes is redefined, a mechanistic model for agmatine-dependent catalysis in alternative spermidine biosynthesis is established, and a testable framework for predicting substrate specificity is provided across this family of bacterial polyamine biosynthetic en...
Johnette Ostlund, Lindsey A. Johnston, Makenzie A. Pardoe et al.
· Journal of Biological Chemis... · 0 citations