In Silico Screening of Philippine Fabaceae-Derived Phenolic Acids as Potential NAGZ (Β-Hexosaminidase) Inhibitors of Neisseria Gonorrhoeae (PDB ID: 6JTJ)
Phenolic acids from Philippine Fabaceae plants were evaluated as potential inhibitors of the NagZ protein, an enzyme essential for bacterial cell wall recycling and survival, and ellagic acid, 3,4-Di-O-caffeoylquinic acid, and 4-caffeoylquinic acid showed the strongest binding and favorable pharmacokinetic properties.