Targeting ERO1α triggers tumor immunosurveillance in triple-negative breast cancer.
Triple-negative breast cancer (TNBC) remains a highly aggressive malignancy with limited responsiveness to immune checkpoint blockade. Here, we identify endoplasmic reticulum oxidoreductase 1 alpha (ERO1α; ERO1A), a key regulator of oxidative protein folding, as a determinant of tumor immunogenicity and immunotherapy r...
Alessandro Cherubini, Ersilia Varone, Sara Irene Malandrin et al.
· Redox Biology · 0 citations