Sep 2026
A nucleolar assembly module integrates an ancestral isoaspartylase to safeguard ribosome biogenesis
A. G. Geiger, Sébastien Favre, Oscar Vadas et al.
· bioRxiv · 0 citations
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Open access
Aug 2026
DNTTIP2 coordinates RNA exosome activities to ensure fidelity of human ribosome assembly
The RNA exosome-associated helicase Mtr4/MTR4 (yeast/human) is recruited by adaptor proteins bearing Arch-Interacting Motifs (AIMs) to selectively degrade RNA substrates. Although the exosome targets diverse RNAs, only a few adaptors have been identified. Here, we extend the inventory of human adaptors to include a pre...
Agnese Pisano, Jessie Bourdeaux, Jarosław Mazur et al.
· Nature Communications · 0 citations