18. DEVELOPMENTAL BOTTLENECK GENES IN DORSOLATERAL PREFRONTAL CORTEX RISK NETWORKS REVEAL SHARED AND DISORDER-SPECIFIC ARCHITECTURE IN SCHIZOPHRENIA AND BIPOLAR DISORDER
Background Schizophrenia (SCZ) and bipolar disorder (BD) genetic risks are highly polygenic and largely non-coding, suggesting that their effects are mediated through gene regulatory networks. However, most studies rely on static models that fail to capture developmental dynamics. We aimed to identify bottleneck genes...
Fabio Di Camillo, Loredana Bellantuono, Nicola Pedreschi et al.
· European Neuropsychopharmaco... · 0 citations