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Author

Daniel Diez-Iriepa

1 paper indexed here

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Open access Sep 2026

MCC950-Derived NLRP3 Inflammasome Inhibitor Modulates Glial Inflammatory Signatures and Neuroinflammation after Traumatic Brain Injury

It is demonstrated that compound 4b exerts NLRP3 inhibitory activity in CNS-resident innate immune cells and modulates neuroinflammation and functional recovery after TBI, supporting its further development as a mechanistically validated NLRP3 inhibitor with translational relevance.

Céline Decouty-Pérez, María Álvarez-Rubal, Icíar Polo-Fernández et al. · 0 citations

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