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Dan-Dan Ye

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Review Open access Oct 2026

The interplay of cGAS-STING and autophagy: bidirectional regulation and pathophysiological implication

The cGAS-STING pathway is a fundamental cytosolic DNA-sensing mechanism that activates innate immune responses through the production of type I interferons (IFNs) and other cytokines. Autophagy, a conserved intracellular degradation system, plays crucial roles in maintaining cellular homeostasis by clearing damaged o...

Dan-Dan Ye, Qiong Li, Amit Sharma et al. · 0 citations

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