Author

Dan-Chen Zhao

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Review Open access Sep 2026

Flavonoids as multi-target protective agents against aflatoxin B1 toxicity: mechanistic convergence and translational challenges

Aflatoxin B1 (AFB1) is the most widespread and toxic mycotoxin found in food and feed. It is both chemically and physically stable and shows resistance to degradation during processing. AFB1 can cause damage to multiple organs, including the liver, immune system, nervous system, kidneys, reproductive system, intestines...

Hua-Hua Shi, Jie Mu, Rong Li et al. · Poultry Science · 0 citations

Review Aug 2026

Chalcone-indole hybrid scaffolds as promising anticancer drug candidates: a mini-review.

Cancer treatment is hampered by severe systemic side effects, poor tumor selectivity, and multidrug resistance (MDR). Molecular hybridization integrates chalcone and indole, two privileged antitumor pharmacophores, into one scaffold to generate chalcone-indole hybrids that synergistically enhance antitumor potency, imp...

Yafei Zhuang, Yanjing Cheng, Dan-Chen Zhao et al. · Future Medicinal Chemistry · 0 citations