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Author

Dan Chen

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Open access Sep 2026

Integrated machine learning and multi-dataset analysis identify SDS as a diagnostic and immune-related hub gene in hepatoblastoma

Integrated machine learning identified CLEC1B, ITGA6, SDS, and TTC36 as robust diagnostic genes for hepatoblastoma and SDS exerts a tumor-suppressive role and is closely linked to the immune microenvironment, making it a promising diagnostic biomarker and therapeutic target in HB.

Dan Chen, Bai-Xue Zhang, Yan-Long Zhang et al. · 0 citations
Open access Sep 2026

TRIM21 blocks DDX3X-driven stress granule formation during Mycobacterium tuberculosis infection via a non-canonical E3 ligase mechanism

The analysis of human TB transcriptomic datasets showed that TRIM21 expression levels correlate with TB progression in human patients and demonstrated that TRIM21 deficiency suppresses Mtb growth in both macrophages and a murine model of tuberculosis (TB).

Rui-Yao Xu, Meng-Ru Lu, Gao-Yan Wang et al. · 0 citations

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