One-Pot Isothermal Linear Amplification and Cas12a-Based Nucleic Acid Detection
CATNAP (Cas trans -nuclease detection of amplified products), a method that integrates isothermal linear DNA amplification with Cas12a detection in a single reaction, bridges the sensitivity gap in CRISPR diagnostics while maintaining simplicity, making accurate disease detection more accessible in resource-limited setti...
Selma Sinan, Remy M. Kooistra, Karunya Rajaraman et al.
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