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Dalton Shepherd

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Review Open access Sep 2026

Rupioid Syphilis Beyond Immunosuppression: A Systematic Review of Cases in HIV-Negative Patients

Rupioid syphilis (malignant syphilis or lues maligna) is a severe ulcero-nodular manifestation of infection originating from Treponema pallidum. It is typically associated with immunosuppressed states, notably those derived from HIV co-infection. This systematic review aims to highlight the rare instances in which this...

Erica K. Rankin, Chad Gentry, Alexandra Daily et al. · 0 citations

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