Open access
Sep 2026
High frame rate in vivo two-photon microscopy to quantify murine cerebrospinal fluid flow heterogeneity
Cerebrospinal fluid (CSF) flows through perivascular spaces (PVSs) surrounding brain vasculature, and impaired flow has been linked to neurodegenerative diseases such as Alzheimer’s. However, the mechanisms driving CSF flow and its oscillatory dynamics remain poorly understood. Using high frame rate two-photon imaging...
Cooper Gray, Kai-Di Hu, Dorothea H. Tse et al.
· bioRxiv · 0 citations