Aug 2026
Electrogenic HfO2/TiO2 Living Biointerface Dismantles Metabolic Radioresistance for Amplified Radio-Immunotherapy
Radiotherapy (RT) efficacy in aggressive solid tumors is hindered by lactate-driven metabolic radioresistance and an immunosuppressive microenvironment. Here, we engineer a living biointerface (SHT) via in situ biomineralization of HfO2/TiO2 onto an electrogenic Shewanella oneidensis chassis to address this multiface...
Men-Gen Guo, Peng-Cheng Sun, Wen-Jie Xu et al.
· ACS Nano · 0 citations