Author

Da-Wei Zhang

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Open access Apr 2026

The Effects of matrix metalloproteinase-14 Inhibition on diabetic Wound Healing

Abstract Matrix metalloproteinases play critical roles in wound repair, yet their context-dependent functions in diabetic wound healing remain elusive. In this study, we found that both the expression and activity of matrix metalloproteinase-14 were significantly elevated in diabetic foot ulcers. Using animal models, w...

Gui-Fen Zeng, Guo-Tian Chen, Zhen Zhou et al. · Experimental and clinical en... · 0 citations

Open access Sep 2026

Glycoside fraction from pear seed functionally antagonizes sFLT-1 and restores angiogenic signaling in preeclampsia.

Preeclampsia is characterized by endothelial dysfunction and angiogenic imbalance driven, in part, by excess soluble fms-like tyrosine kinase-1 (sFLT-1). Building on previous findings demonstrating vascular modulatory effects of cardiac and quercetin glycosides from Dacryodes edulis seeds during L-NAME-induced vascular...

P. Amadi, J. O. Osuoha, A. J. Ogbolosingha et al. · Hypertension Research · 0 citations