Author

Da-Qiang Zhao

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Review Open access Jul 2026

Antibody-oligonucleotide conjugates: design principles, intracellular delivery, and translational opportunities

The intracellular fate of AOCs is discussed and endosomal escape is highlighted as a major rate limiting step that often constrains biological activity despite efficient cellular uptake.

Yuqian Li, Xinlin Liu, Fuyuan Zhang et al. · Journal of Hematology & Onco... · 0 citations