Dajiang Zhu

Three-hinge gyri link individualized folding topology to cortical and superficial white-matter diffusion organization

Individual differences in cortical folding are a hallmark of human brain anatomy, but what this variability reflects in the underlying tissue remains unclear. Three-hinge gyri (3HGs), where three gyral crests converge, provide an individualized higher-order folding landmark for probing this relationship. Using 7T diffu...

Grow2Fold: mapping heterogeneous developmental growth to human brain folding

Biophysical modeling of anatomically realistic prenatal cortical folding development

A whole-brain developmental framework that integrates region-specific, data-driven growth laws with anatomically realistic cortical geometry to enable biologically interpretable modeling of cortical morphogenesis during gestation is introduced.