Author

Da-Hyun Kim

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Review Open access Aug 2026

Human iPSC-derived vascularized organoids: strategy-based insights from 2D endothelial cells to 3D blood vessel organoids

Organoids derived from human pluripotent stem cells (PSCs) have emerged as powerful in vitro models for studying development, disease, and therapeutic responses, yet their lack of functional vasculature limits growth, maturation, and physiological relevance. Early vascularization strategies relied on human umbilical ve...

Seo-Yeon Kong, Da-Hyun Kim · Biofabrication · 1 citation

Open access Aug 2026

Leveraging IGF signaling to improve the spatial organization and regenerative potential of iPSC-derived vascularized liver organoids

Vascularized liver organoids are developed by integrating human induced pluripotent stem cell (iPSC)–derived hepatoblasts and endothelial cells into decellularized scaffolds functionalized with an anti-CD31 aptamer–based vascular coating agent (VCA) to establish a comprehensive framework for generating physiologically...

Da-Hyun Kim, Yongju Lee, Min-Ji Kim et al. · Science Advances · 1 citation